The pharmaceutical excipient PEG400 affect the absorption of baicalein in Caco‐2 monolayer model by interacting with UDP‐glucuronosyltransferases and efflux transport proteins-Reference-Cited by-同舟云学术

The pharmaceutical excipient PEG400 affect the absorption of baicalein in Caco‐2 monolayer model by interacting with UDP‐glucuronosyltransferases and efflux transport proteins

Published:2022-02 Issue:1 Volume:10 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacology Res & Perspec

Author:

Cao Siyuan¹²,Zhang Min¹,Yuan Minyan¹²,Yang Dan¹²,Zhao Mei¹²,Zhang Shuo²³,Wang Pengjiao¹,Zhang Rongping⁴,Gao Xiuli¹²^ORCID

Affiliation:

1. State Key Laboratory of Functions and Applications of Medicinal Plants and School of Pharmacy Guizhou Medical University Guiyang China

2. Department of Education of Guizhou Center of Microbiology and Biochemical Pharmaceutical Engineering Guiyang China

3. Experimental Animal Center of Guizhou Medical University Guiyang China

4. School of Pharmacy Kunming Medical University Kunming China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.928

Reference31 articles.

1. Potential for pharmaceutical excipients to impact absorption: A mechanistic review for BCS Class 1 and 3 drugs

2. Excipient-drug pharmacokinetic interactions: Effect of disintegrants on efflux across excised pig intestinal tissues

3. Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration

4. Boosting drug bioavailability in men but not women through the action of an excipient

5. Pharmacokinetic Study of Bioactive Flavonoids in the Traditional Japanese Medicine Keigairengyoto Exerting Antibacterial Effects against Staphylococcus aureus

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