Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease-Reference-Cited by-同舟云学术

Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease

Published:2022-01-27 Issue:11 Volume:18 Page:2117-2130
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Caldwell Andrew B.¹^ORCID,Liu Qing²³^ORCID,Zhang Can⁴^ORCID,Schroth Gary P.⁵^ORCID,Galasko Douglas R.²^ORCID,Rynearson Kevin D.²^ORCID,Tanzi Rudolph E.⁴^ORCID,Yuan Shauna H.²⁶^ORCID,Wagner Steven L.²⁷^ORCID,Subramaniam Shankar¹⁸⁹¹⁰^ORCID

Affiliation:

1. Department of Bioengineering University of California, San Diego La Jolla California USA

2. Department of Neurosciences University of California, San Diego La Jolla California USA

3. Department of Obstetrics, Gynecology, and Reproductive Sciences University of California, San Diego La Jolla California 92093 USA

4. Genetics and Aging Research Unit, Department of Neurology Massachusetts General Hospital Charlestown Massachusetts USA

5. Illumina, Inc. San Diego California USA

6. N. Bud Grossman Center for Memory Research and Care Department of Neurology, University of Minnesota, Minneapolis, MN, USA; GRECC, Minneapolis VA Health Care System Minneapolis MN USA

7. VA San Diego Healthcare System La Jolla California USA

8. Department of Cellular and Molecular Medicine University of California, San Diego La Jolla California USA

9. Department of Nanoengineering University of California, San Diego La Jolla California USA

10. Department of Computer Science and Engineering University of California, San Diego La Jolla California USA

Funder

Cure Alzheimer's Fund

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12553

Reference61 articles.

1. The Genetics of Alzheimer Disease

2. Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

3. Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective

4. Increased in Vivo Amyloid-β42 Production, Exchange, and Loss in Presenilin Mutation Carriers

5. Safety and Tolerability of the γ-Secretase Inhibitor Avagacestat in a Phase 2 Study of Mild to Moderate Alzheimer Disease

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