Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing

Author:

Chen Chao123,Posocco Paola45,Liu Xiaoxuan16,Cheng Qiang7,Laurini Erik4,Zhou Jiehua8,Liu Cheng13,Wang Yang1,Tang Jingjie1,Col Valentina Dal4,Yu Tianzhu3,Giorgio Suzanne1,Fermeglia Maurizio4,Qu Fanqi3,Liang Zicai7,Rossi John J.89,Liu Minghua10,Rocchi Palma6,Pricl Sabrina45,Peng Ling1

Affiliation:

1. Aix-Marseille Université; CNRS; Centre Interdisciplinaire de Nanoscience de Marseille; UMR 7325; Equipe Labellisée Ligue Contre le Cancer; 13288 Marseille France

2. Aix-Marseille Université; CNRS; Institut de Chimie Radicalaire, UMR 7273; 13390 Marseille France

3. College of Chemistry and Molecular Sciences; Wuhan University; Wuhan 430072 P. R. China

4. Molecular Simulation Engineering (MOSE) Laboratory; Department of Engineering and Architecture (DEA); University of Trieste; Piazzale Europa 1 34127 Trieste Italy

5. National Interuniversity Consortium for Material Science and Technology (INSTM); Research Unit MOSE-DEA; University of Trieste; Trieste 34127 Italy

6. Centre de Recherche en Cancérologie de Marseille; Inserm, UMR 1068; CNRS UMR 7258, Aix Marseille Université U105; Institut Paoli Calmettes 13009 Marseille France

7. Laboratory of Nucleic Acid Technology; Institute of Molecular Medicine; Peking University; 100871 Beijing China

8. Department of Molecular and Cellular Biology; Beckman Research Institute; CA 91010 USA

9. Irell and Manella Graduate School of Biological Sciences; Beckman Research Institute; CA 91010 USA

10. Beijing National Laboratory for Molecular Sciences; CAS Key Laboratory of Colloids and Surfaces; Institute of Chemistry; Chinese Academy of Sciences; Beijing 100190 China

Funder

ESTECO s.r.l

University of Trieste

HPC Italian Supercomputing Resource Allocation

Publisher

Wiley

Subject

Biomaterials,Biotechnology,General Materials Science,General Chemistry

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