The change in nasal inflammatory markers after intranasal challenges with particulate chitin and lipopolysaccharide: a randomized, double-blind, placebo-controlled, crossover study with a positive control

Author:

Sigsgaard Torben1,Thorne Peter S.2,Schlünssen Vivi1,Bønløkke Jakob1,Riddervold Ingunn S.1,Hoppe Kimberly A.2,Andersen Niels Trolle3,Mackenzie Neill M.4

Affiliation:

1. Section of Environment, Occupation and Health; Department of Public Health, University of Aarhus; Aarhus Denmark

2. College of Public Health; Department of Occupational and Environmental Health, University of Iowa; Iowa City IA

3. Section of Biostatistics; Department of Public Health, University of Aarhus; Aarhus Denmark

4. Roji Ltd; Welwyn Garden City Hertfordshire UK

Funder

CMP Therapeutics Ltd, Biopark Hertfordhsire, UK

Publisher

Wiley

Subject

Otorhinolaryngology,Immunology and Allergy

Reference26 articles.

1. CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation;Hansen;J Clin Invest,2000

2. Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: role of CD8+ T cells and IL-18;Hansen;J Immunol,2000

3. Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides;Sur;J Immunol,1999

4. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice;Broide;J Immunol,1998

5. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma;Kline;J Immunol,1998

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