Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: In vitro and in vivo correlation-Reference-Cited by-同舟云学术

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Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: In vitro and in vivo correlation

Published:2015-01-14 Issue:4 Volume:55 Page:467-477
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Sabo John P.¹,Kort Jens¹,Ballow Charles²,Kashuba Angela D.M.³,Haschke Manuel⁴,Battegay Manuel⁴,Girlich Birgit⁵,Ting Naitee¹,Lang Benjamin⁶,Zhang Wei¹,Cooper Curtis⁷,O'Brien Drané¹,Seibert Eleanore¹,Chan Tom S.¹,Tweedie Donald¹,Li Yongmei¹

Affiliation:

1. Boehringer Ingelheim Pharmaceuticals, Inc.; Ridgefield CT USA

2. Buffalo Clinical Research Center; Buffalo NY USA

3. University of North Carolina; Chapel Hill NC USA

4. University Hospital Basel; Basel Switzerland

5. Boehringer Ingelheim (Schweiz) GmbH; Basel Switzerland

6. Boehringer Ingelheim Pharmaceuticals GmbH & Co. KG; Biberach Germany

7. The Ottawa Hospital; Ottawa ON Canada

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference27 articles.

1. Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease;White;Antimicrob Agents Chemother,2010

2. Potency, safety, and pharmacokinetics of the NS3/4A protease inhibitor BI201335 in patients with chronic HCV genotype-1 infection;Manns;J Hepatol,2011

3. Faldaprevir combined with peginterferon alfa-2a and ribavirin in chronic hepatitis C virus genotype-1 patients with prior nonresponse: SILEN-C2 trial;Sulkowski;Hepatology,2013

4. Faldaprevir combined with pegylated interferon alfa-2a and ribavirin in treatment-naïve patients with chronic genotype 1 HCV: SILEN-C1 trial;Sulkowski;Hepatology,2013

5. SILEN-C3, a phase 2 randomized trial with faldaprevir plus pegylated interferon α-2a and ribavirin in treatment-naive hepatitis C virus genotype 1-infected patients;Dieterich;Antimicrob. Agents Chemother,2014

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1. Combined Oral Contraceptives As Victims of Drug Interactions;Drug Metabolism and Disposition;2023-03-24

2. Effect of itraconazole on the pharmacokinetics of faldaprevir in healthy subjects;PHARMAZIE;2021

3. Aproximación para establecer y evaluar la relevancia clínica de las interacciones medicamentosas en el tratamiento de pacientes infectados con virus de hepatitis C, revisión estructurada (actualización 2015 – 2017);Revista Colombiana de Gastroenterología;2019-07-02

4. Transcriptomic analysis of cells in response to EV71 infection and 2Apro as a trigger for apoptosis via TXNIP gene;Genes & Genomics;2018-11-29

5. Pharmacokinetic Interaction between Faldaprevir and Cyclosporine or Tacrolimus in Healthy Volunteers: A Prospective, Open-Label, Fixed-Sequence, Crossover Study;Basic & Clinical Pharmacology & Toxicology;2018-03-30

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