Pharmacokinetic Interaction between Faldaprevir and Cyclosporine or Tacrolimus in Healthy Volunteers: A Prospective, Open-Label, Fixed-Sequence, Crossover Study

Author:

Huang Fenglei1,Voelk Claudia2,Trampisch Matthias3,Rowland Lois1,Schultz Armin4,Sabo John P.1

Affiliation:

1. Boehringer Ingelheim Pharmaceuticals, Inc.; Ridgefield CT USA

2. Boehringer Ingelheim Pharma GmbH & Co. KG; Biberach Germany

3. Boehringer Ingelheim Pharma GmbH & Co. KG; Ingelheim Germany

4. CRS Clinical Research Services Mannheim GmbH; Mannheim Germany

Funder

Boehringer Ingelheim

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Reference61 articles.

1. Recurrence of hepatitis C after liver transplantation;Vinaixa;Ann Gastroenterol,2013

2. Trek Therapeutics P A study of faldaprevir, ribavirin and TD-6450 in participants with genotype 4 hepatitis C virus infection http://clinicaltrials.gov/show/NCT02593162

3. Trek Therapeutics P A study of faldaprevir, TD-6450 and other antivirals in participants with genotype 1b hepatitis C virus infection http://clinicaltrials.gov/show/NCT02716428

4. Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease;White;Antimicrob Agents Chemother,2010

5. STARTVerso1: a randomized trial of faldaprevir plus pegylated interferon/ribavirin for chronic HCV genotype-1 infection;Ferenci;J Hepatol,2015

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