Synthesis of deuterated 1,2,3,4-tetrahydroisoquinolines
Author:
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry
Reference23 articles.
1. Genetic variation in the human hepatic cytochrome P-450 system
2. 1,2,3,4-Tetrahydroisoquinoline Derivatives with Antihypertensive Properties
3. Determination of debrisoquin and its 4-hydroxy metabolite in plasma by gas chromatography/mass spectrometry
4. Preparation of cis- and trans-Decahydroisoquinolines and of Bz-Tetrahydroisoquinoline
5. A selective method for deuterium exchange in hydroaromatic compounds
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1. One-pot H/D exchange and low-coordinated iron electrocatalyzed deuteration of nitriles in D2O to α,β-deuterio aryl ethylamines;Nature Communications;2022-10-10
2. Tandem H/D Exchange-SET Reductive Deuteration Strategy for the Synthesis of α,β-Deuterated Amines Using D2O;The Journal of Organic Chemistry;2021-08-20
3. “Methylene Bridge” to 5-HT3 Receptor Antagonists: Conformationally Constrained Phenylguanidines;ACS Chemical Neuroscience;2018-10-30
4. Regioselective Access to 3-Aryl-1-aminoisoquinolines via Nickel(I)-Catalyzed C–C and C–N Cascade Coupling Reactions from the Substituted 2-(Cyanomethyl)benzonitriles;The Journal of Organic Chemistry;2018-08-14
5. Deuteration and fluorination of 1,3-bis(2-phenylethyl)pyrimidine-2,4,6(1H,3H,5H)-trione to improve its pharmacokinetic properties;Bioorganic & Medicinal Chemistry Letters;2014-11
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