Population pharmacokinetic-pharmacodynamic modeling of omecamtiv mecarbil, a cardiac myosin activator, in healthy volunteers and patients with stable heart failure-Reference-Cited by-同舟云学术

Population pharmacokinetic-pharmacodynamic modeling of omecamtiv mecarbil, a cardiac myosin activator, in healthy volunteers and patients with stable heart failure

Published:2015-07-14 Issue:11 Volume:55 Page:1236-1247
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:J Clin Pharmacol

Author:

Vu Thuy¹,Ma Peiming¹²,Xiao Jim J.¹³,Wang Yow-Ming C.¹⁴,Malik Fady I.⁵,Chow Andrew T.¹

Affiliation:

1. Clinical Pharmacology, M&S, Medical Sciences; Amgen Inc.; Thousand Oaks CA USA

2. Current address: GlaxoSmith Kline; Shanghai China

3. Current address: Clovis Oncology; San Francisco CA USA

4. Current address: Office of Clinical Pharmacology; Food and Drug Administration; Silver Spring MD USA

5. Cytokinetics Inc.; South San Francisco CA USA

Funder

Amgen, Inc.

Cytokinetics

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.538/fullpdf

Reference26 articles.

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3. Agents with inotropic properties for the management of acute heart failure syndromes. Traditional agents and beyond;Teerlink;Heart Fail Rev,2009

4. Cardiac inotropes: current agents and future directions;Hasenfuss;Eur Heart J,2011

5. Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial;Cuffe;JAMA,2002

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