Contribution of equilibrative nucleoside transporter(s) to intestinal basolateral and apical transports of anticancer trifluridine

Author:

Takahashi Koichi12ORCID,Yoshisue Kunihiro1,Chiba Masato1,Nakanishi Takeo2,Tamai Ikumi2

Affiliation:

1. Pharmacokinetics Research Laboratories, Discovery and Preclinical Research Division; Taiho Pharmaceutical Co. Ltd; Tsukuba Ibaraki Japan

2. Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences; Kanazawa University; Kakuma-machi Kanazawa Japan

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference22 articles.

1. Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line;Crawford;Journal of Biological Chemistry,1998

2. In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans;Dawson;Drug Metabolism and Disposition,2012

3. Phase I study of TAS-102 treatment in Japanese patients with advanced solid tumours;Doi;British Journal of Cancer,2012

4. An optimal dosing schedule for a novel combination antimetabolite, TAS-102, based on its intracellular metabolism and its incorporation into DNA;Emura;International Journal of Molecular Medicine,2004

5. In situ hybridization and immunolocalization of concentrative and equilibrative nucleoside transporters in the human intestine, liver, kidneys, and placenta;Govindarajan;American Journal of Physiology Regulatory Integrative Comparative Physiology,2007

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