Optimized Synthesis of AMPA Receptor Antagonist ZK 187638 and Neurobehavioral Activity in a Mouse Model of Neuronal Ceroid Lipofuscinosis-Reference-Cited by-同舟云学术

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Optimized Synthesis of AMPA Receptor Antagonist ZK 187638 and Neurobehavioral Activity in a Mouse Model of Neuronal Ceroid Lipofuscinosis

Published:2006-10-13 Issue:10 Volume:1 Page:1142-1148
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Elger Bernd,Schneider Matthias,Winter Eric,Carvelli Lucia,Bonomi Marco,Fracasso Claudia,Guiso Giovanna,Colovic Milena,Caccia Silvio,Mennini Tiziana

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference40 articles.

1. Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders

2. in Excitotoxicity in neurological diseases. New therapeutic challenge (Eds.: ), Kluwer Academic Publishers, Boston, 2004, p. 217.

3. Motor Neurons Are Selectively Vulnerable to AMPA/Kainate Receptor-Mediated InjuryIn Vitro

4. Novel α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionate (AMPA) Receptor Antagonists of 2,3-Benzodiazepine Type: Chemical Synthesis, in Vitro Characterization, and in Vivo Prevention of Acute Neurodegeneration

5. The neuronal ceroid lipofuscinoses in human EPMR and mnd mutant mice are associated with mutations in CLN8

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2. AAV9 Gene Therapy Increases Lifespan and Treats Pathological and Behavioral Abnormalities in a Mouse Model of CLN8-Batten Disease;Molecular Therapy;2021-01

3. Neuronal Ceroid Lipofuscinosis: Potential for Targeted Therapy;Drugs;2020-11-26

4. AAV9 gene therapy restores lifespan and treats pathological and behavioral abnormalities in a mouse model of CLN8-Batten disease;2020-05-06

5. The neuronal ceroid-lipofuscinoses (Batten disease);Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease;2020

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