The First Potent Subtype-Selective Retinoid X Receptor (RXR) Agonist Possessing a 3-Isopropoxy-4-isopropylphenylamino Moiety, NEt-3IP (RXRα/β-dual agonist)-Reference-Cited by-同舟云学术

The First Potent Subtype-Selective Retinoid X Receptor (RXR) Agonist Possessing a 3-Isopropoxy-4-isopropylphenylamino Moiety, NEt-3IP (RXRα/β-dual agonist)

Published:2008-05-19 Issue:5 Volume:3 Page:780-787
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Takamatsu Kayo,Takano Atsushi,Yakushiji Nobumasa,Morohashi Kazunori,Morishita Ken-ichi,Matsuura Nobuyasu,Makishima Makoto,Tai Akihiro,Sasaki Kenji,Kakuta Hiroki

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference21 articles.

1. RAR and RXR modulation in cancer and metabolic disease

2. Design of selective nuclear receptor modulators: RAR and RXR as a case study

3. 9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers

4. A Selective Retinoid X Receptor Agonist Bexarotene (Targretin) Prevents and Overcomes Acquired Paclitaxel (Taxol) Resistance in Human Non–Small Cell Lung Cancer

Cited by 52 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural basis for the full and partial agonist activities of retinoid X receptor α ligands with an iso-butoxy and an isopropyl group;Biochemical and Biophysical Research Communications;2024-11

2. Rational design and virtual screening identify mimetics of the RXR agonist valerenic acid;ChemMedChem;2024-01-31

3. Retinoid X Receptor agonists as selective modulators of the immune system for the treatment of cancer;Pharmacology & Therapeutics;2023-12

4. Characterization and Interconversion of Two Crystal Forms of NEt-3IB, a Retinoid X Receptor Agonist;Chemical and Pharmaceutical Bulletin;2023-04-01

5. Ligand Screening System for the RXRα Heterodimer Using the Fluorescence RXR Agonist CU-6PMN;ACS Medicinal Chemistry Letters;2023-02-20