EPHA2 blockade reverses acquired resistance to afatinib induced by EPHA2‐mediated MAPK pathway activation in gastric cancer cells and avatar mice-Reference-Cited by-同舟云学术

EPHA2 blockade reverses acquired resistance to afatinib induced by EPHA2‐mediated MAPK pathway activation in gastric cancer cells and avatar mice

Published:2019-11 Issue:9 Volume:145 Page:2440-2449
ISSN:0020-7136
Container-title:International Journal of Cancer
language:en
Short-container-title:Int. J. Cancer

Author:

Chen Zuhua¹,Liu Zhentao¹,Zhang Mengqi¹,Huang Wenwen¹,Li Zhongwu²,Wang Shubin³,Zhang Cheng¹,Dong Bin²,Gao Jing¹³,Shen Lin¹³^ORCID

Affiliation:

1. Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal OncologyPeking University Cancer Hospital & Institute Beijing China

2. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of PathologyPeking University Cancer Hospital & Institute Beijing China

3. Department of OncologyPeking University Shenzhen Hospital Shenzhen Guangdong China

Funder

National Key Research and Development Program of China

Publisher

Wiley

Subject

Cancer Research,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.32313

Reference38 articles.

1. Cell Signaling by Receptor Tyrosine Kinases

2. ErbB/HER protein-tyrosine kinases: Structures and small molecule inhibitors