EGFR-mutant non-small cell lung cancer patients harboring CDK4 amplification show favorable response to afatinib: Two case reports-Reference-Cited by-同舟云学术

EGFR-mutant non-small cell lung cancer patients harboring CDK4 amplification show favorable response to afatinib: Two case reports

Published:2024-05-21 Issue:12 Volume:137 Page:1465-1467
ISSN:0366-6999
Container-title:Chinese Medical Journal
language:en
Short-container-title:

Author:

Zhan Shuting¹,Cheng Bo¹,Liu Xiwen¹,Li Jianfu¹,Bai Ge²,Cai Qi¹,Wang Huiting¹,Xiang Yang¹,Li Chunyan¹,He Jianxing¹³,Liang Wenhua¹⁴

Affiliation:

1. Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University & Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, Guangdong 510120, China

2. National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health & The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China

3. Southern Medical University, Guangzhou, Guangdong 510120, China

4. Department of Respiratory and Critical Care Medicine, The Tenth Affiliated Hospital of Southern Medical University, Dongguan, Guangdong 523108, China

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference5 articles.

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3. EPHA2 blockade reverses acquired resistance to afatinib induced by EPHA2-mediated MAPK pathway activation in gastric cancer cells and avatar mice;Chen;Int J Cancer,2019

4. Mouse avatar models of esophageal squamous cell carcinoma proved the potential for EGFR-TKI afatinib and uncovered Src family kinases involved in acquired resistance;Liu;J Hematol Oncol,2018

5. A next generation connectivity map: L1000 platform and the first 1,000,000 profiles;Subramanian;Cell,2017