Modification of γ‐secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease-Reference-Cited by-同舟云学术

Modification of γ‐secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

Published:2012-05-02 Issue:7 Volume:4 Page:660-673
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Guix Francesc X.¹²,Wahle Tina¹²,Vennekens Kristel¹²,Snellinx An¹²,Chávez‐Gutiérrez Lucía¹²,Ill‐Raga Gerard³,Ramos‐Fernandez Eva³,Guardia‐Laguarta Cristina⁴,Lleó Alberto⁴,Arimon Muriel⁵,Berezovska Oksana⁵,Muñoz Francisco J.³,Dotti Carlos G.¹²⁶,De Strooper Bart¹²

Affiliation:

1. VIB Center for Biology of Disease – VIB, Leuven, Belgium

2. Center of Human Genetics and Leuven Institute for Neurodegenerative Diseases (LIND), KULeuven, Leuven, Gasthuisberg O&N, Belgium

3. Laboratory of Molecular Physiology and Channelopathies, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain

4. Alzheimer Laboratory, Neurology Department, Hospital de la Santa Creu i Sant Pau, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain

5. Alzheimer Research Unit, MassGeneral Institute for Neurodegenerative Diseases, Massachusetts General Hospital, Charlestown, MA, USA

6. Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Madrid, Spain

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/emmm.201200243

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1. Aging in a dish: Age‐dependent changes of neuronal survival, protein oxidation, and creatine kinase BB expression in long‐term hippocampal cell culture

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3. Elevated oxidative stress in models of normal brain aging and Alzheimer's disease