Effects of a recombinant humanized anti‐cocaine monoclonal antibody on the metabolism and distribution of cocaine in vitro and in mice
Author:
Affiliation:
1. Department of Pharmacology & Systems Physiology, College of Medicine University of Cincinnati Cincinnati Ohio USA
2. Department of Pathology & Laboratory Medicine, College of Medicine University of Cincinnati Cincinnati Ohio USA
Funder
National Institute on Drug Abuse
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.1009
Reference16 articles.
1. Recent Increases in Cocaine-Related Overdose Deaths and the Role of Opioids
2. A Recombinant Humanized Anti-Cocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Rats
3. A Chimeric Human/Murine Anticocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Mice
4. Characterization of a recombinant humanized anti-cocaine monoclonal antibody produced from multiple clones for the selection of a master cell bank candidate
5. The effects of a repeated dose of a recombinant humanized anti-cocaine monoclonal antibody on cocaine self-administration in rats
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1. Toxicokinetics of a humanized anti-cocaine monoclonal antibody in male and female rats and lack of cross-reactivity;Human Vaccines & Immunotherapeutics;2023-11-08
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3. Reformulation and Thermal Stability of a Therapeutic Anti-Cocaine mAb;Journal of Pharmaceutical Sciences;2023-06
4. A humanized anti‐cocaine mAb antagonizes the cardiovascular effects of cocaine in rats;Pharmacology Research & Perspectives;2023-01-11
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