Monoclonal War: The Antibody Arsenal and Targets for Expanded Application-Reference-Cited by-同舟云学术

Monoclonal War: The Antibody Arsenal and Targets for Expanded Application

Published:2023-09-20 Issue:3 Volume:3 Page:346-357
ISSN:2673-5601
Container-title:Immuno
language:en
Short-container-title:Immuno

Author:

Rosenn Eric H.¹^ORCID,Benhaim Mickael²,Siegel Allison²,Stein David A.²^ORCID,Leonard Joseph S.²,Katcher Erik²,Halperin Dania²,Mostel Zachary³

Affiliation:

1. Department of Biomedical Engineering, Boston University School of Engineering, Boston, MA 02215, USA

2. School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel

3. Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA

Abstract

Advancements in sequencing and screening technology have made monoclonal antibodies more accessible, cost-effective, and precise. These drugs effectively target pathogens and cancer cells and even regulate metabolic pathways by focusing on specific intermediates. Monoclonal antibodies play a key role in mitigating a rise in occupation-related cancers, neurodegenerative disorders, and multidrug-resistant organisms. Here, we review the origins, mechanisms, and applications of this important drug class and explore future avenues for research.

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2673-5601/3/3/21/pdf

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