Secondary metabolites from a marine sponge‐associated fungus Xenomyrothecium sp. IMBC‐FP2.11

Author:

Quang Tran Hong1ORCID,Huong Pham Thi Mai1,Ngan Nguyen Thi Thanh2,Hanh Tran Thi Hong1,Cuong Nguyen Xuan1ORCID,Nam Nguyen Hoai1,Van Minh Chau1

Affiliation:

1. Institute of Marine Biochemistry Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

2. Institute of Genome Research VAST, 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

Abstract

AbstractIn the study, seven compounds were isolated from an EtOAc extract of the marine‐derived fungal strain Xenomyrothecium sp. IMBC‐FP2.11, including (3R,4R)‐4‐hydroxymellein (1), (3R,4S)‐4‐hydroxymellein (2), trans‐3,4‐dihydro‐3,4,8‐trihydroxynaphtalen‐1(2H)‐one (3), (3S)‐6‐hydroxy‐8‐methoxy‐3,5‐dimethyl‐isochroman (4), 8‐hydroxy‐6‐methyl‐9‐oxo‐9H‐xanthene‐1‐carboxylate (5), TMC‐256A1 (6), and ω‐hydroxyemodin (7). Their chemical structures were elucidated by detailed analysis of the 1D and 2D NMR and mass spectra as well as comparison with those of the previously reported compounds. This is the first case to report the chemical profile of a Xenomyrothecium fungal strain.

Publisher

Wiley

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