Herrmananes A and B, two new sulfated hydrocarbons from the sea cumber <i>Stichopus herrmanni</i>-Reference-Cited by-同舟云学术

Herrmananes A and B, two new sulfated hydrocarbons from the sea cumber Stichopus herrmanni

Published:2022-09-21 Issue:5 Volume:60 Page:685-687
ISSN:2572-8288
Container-title:Vietnam Journal of Chemistry
language:en
Short-container-title:Vietnam Journal of Chemistry

Author:

Vien Le Thi¹,Hanh Tran Thi Hong¹,Quang Tran Hong¹^ORCID,Van Thanh Nguyen¹,Cuong Nguyen Xuan¹^ORCID,Nam Nguyen Hoai¹

Affiliation:

1. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology Hanoi 10072 Viet Nam

Abstract

AbstractUsing various chromatographic separations, two new sulfated hydrocarbons namely herrmananes A and B (1 and 2) were isolated from the aqueous fraction of the methanol residue of the sea cucumber Stichopus herrmanni. Their chemical structures were elucidated by extensive analysis of the 1D, 2D NMR and HR‐QTOF mass spectra. In addition, compound 1 showed significant cytotoxicity on SK‐Mel‐2 cell line with IC50 value of 23.12 ± 1.87 μM, whereas 2 exhibited moderate effect on this cell line with IC50 value of 55.28 ± 4.17 μM.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/vjch.202200095

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