Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes-Reference-Cited by-同舟云学术

Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Published:2021-11-26 Issue:2 Volume:61 Page:
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angewandte Chemie Intl Edit

Author:

Livesley Sarah¹,Sterling Alistair J.²^ORCID,Robertson Craig M.¹^ORCID,Goundry William R. F.³^ORCID,Morris James A.⁴,Duarte Fernanda²^ORCID,Aïssa Christophe¹^ORCID

Affiliation:

1. Department of Chemistry University of Liverpool Crown Street Liverpool L69 7ZD UK

2. Chemistry Research Laboratory University of Oxford 12 Mansfield Road Oxford OX1 3TA UK

3. Early Chemical Development Pharmaceutical Sciences, R&D AstraZeneca Macclesfield SK10 2NA UK

4. Syngenta International Research Centre Bracknell Berkshire RG42 6EY UK

Funder

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202111291

Reference82 articles.

2. U-87947E, a protein quinolone antibacterial agent incorporating a bicyclo[1.1.1]pent-1-yl (BCP) subunit

3. Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based ω-acidic amino acids as glutamate receptors ligands

4. Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

5. Evaluation oftert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

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