Bispecific Aptamer Chimeras Enable Targeted Protein Degradation on Cell Membranes-Reference-Cited by-同舟云学术

Bispecific Aptamer Chimeras Enable Targeted Protein Degradation on Cell Membranes

Published:2021-04-07 Issue:20 Volume:60 Page:11267-11271
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Miao Yanyan¹,Gao Qianqian¹,Mao Menghan¹,Zhang Chao¹,Yang Liqun¹,Yang Yang²,Han Da¹^ORCID

Affiliation:

1. Institute of Molecular Medicine and Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine State Key Laboratory of Oncogenes and Related Genes Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200127 China

2. Department of Thoracic Surgery, Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai 200433 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202102170

Reference38 articles.

1. Tissue-based map of the human proteome

2. Drugging Membrane Protein Interactions

3. Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

4. PROTACs and Other Chemical Protein Degradation Technologies for the Treatment of Neurodegenerative Disorders

5. The current state and future directions of RNAi-based therapeutics

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