The Essential Role of Water Molecules in the Reaction Mechanism of Protein <i>O‐</i> Fucosyltransferase 2-Reference-Cited by-同舟云学术

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The Essential Role of Water Molecules in the Reaction Mechanism of Protein O‐ Fucosyltransferase 2

Published:2022-11-10 Issue:48 Volume:61 Page:
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew Chem Int Ed

Author:

Sanz‐Martínez Ignacio¹^ORCID,García‐García Ana¹,Tejero Tomás²^ORCID,Hurtado‐Guerrero Ramón¹³⁴^ORCID,Merino Pedro¹^ORCID

Affiliation:

1. Instituto de Biocomputación y Física de Sistemas Complejos (BIFI). Universidad de Zaragoza 50018 Zaragoza Spain

2. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH). Universidad de Zaragoza-CSIC 50009 Zaragoza Spain

3. Copenhagen Center for Glycomics Department of Cellular and Molecular Medicine University of Copenhagen Copenhagen DK-2200 Denmark

4. Fundación ARAID Zaragoza 50018 Spain

Funder

Ministerio de Ciencia e Innovación

Gobierno de Aragón

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202213610

Reference25 articles.

1. Biological functions of fucose in mammals

2. A perspective on structural and mechanistic aspects of protein O-fucosylation

3. Crystal structure of the TSP-1 type 1 repeats

4. Structure of human POFUT2: insights into thrombospondin type 1 repeat fold andO-fucosylation

5. A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2

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