Asymmetric Reductive and Alkynylative Heck Bicyclization of Enynes to Access Conformationally Restricted Aza[3.1.0]bicycles-Reference-Cited by-同舟云学术

Asymmetric Reductive and Alkynylative Heck Bicyclization of Enynes to Access Conformationally Restricted Aza[3.1.0]bicycles

Published:2020-04-30 Issue:27 Volume:59 Page:10814-10818
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Huang Xiaolei¹^ORCID,Nguyen Minh Hieu¹,Pu Maoping²,Zhang Luoqiang³^ORCID,Chi Yonggui Robin¹^ORCID,Wu Yun‐Dong⁴^ORCID,Zhou Jianrong Steve³^ORCID

Affiliation:

1. Division of Chemistry and Biological ChemistrySchool of Physical and Mathematical SciencesNanyang Technological University 21 Nanyang Link 637371 Singapore Singapore

2. Shenzhen Bay Laboratory Shenzhen 518055 China

3. State Key Laboratory of Chemical OncogenomicsKey Laboratory of Chemical GenomicsSchool of Chemical Biology and BiotechnologyPeking University Shenzhen Graduate School 2199 Lishui Road, Room F312 Nanshan District Shenzhen 518055 China

4. Lab of Computational Chemistry and Drug DesignState Key Laboratory of Chemical OncogenomicsPeking University Shenzhen Graduate SchoolShenzhen Bay Laboratory Shenzhen 518055 China

Funder

Science and Engineering Research Council

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202000859

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1. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

3. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success