NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment-Reference-Cited by-同舟云学术

NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment

Published:2021-10-27 Issue:48 Volume:60 Page:25428-25435
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Cantrelle François‐Xavier¹²^ORCID,Boll Emmanuelle¹²,Brier Lucile³⁴,Moschidi Danai¹²^ORCID,Belouzard Sandrine⁵^ORCID,Landry Valérie³⁴^ORCID,Leroux Florence³⁴^ORCID,Dewitte Frédérique¹²,Landrieu Isabelle¹²^ORCID,Dubuisson Jean⁵^ORCID,Deprez Benoit³⁴^ORCID,Charton Julie³⁴^ORCID,Hanoulle Xavier¹²^ORCID

Affiliation:

1. CNRS ERL9002—BSI—Integrative Structural Biology 50 avenue Halley F-59658 Villeneuve d'Ascq Lille France

2. Univ. Lille INSERM CHU Lille Institut Pasteur de Lille U1167—RID-AGE—Risk Factors and Molecular Determinants of Aging-Related Diseases 1 rue du Professeur Calmette F-59019 Lille France

3. Univ. Lille INSERM Institut Pasteur de Lille U1177—Drugs and Molecules for Living Systems F-59000 Lille France

4. European Genomic Institute for Diabetes EGID University of Lille 3 rue du Professeur Laguesse F-59006 Lille France

5. Univ. Lille CNRS INSERM, CHU Lille Institut Pasteur de Lille U1019-UMR 9017—CIIL—Center for Infection and Immunity of Lille 1 rue du Professeur Calmette F-59019 Lille France

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202109965

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