Structural elucidation of new urinary tamoxifen metabolites by liquid chromatography quadrupole time-of-flight mass spectrometry

Author:

Lu Jianghai1,He Chunji1,He Genye1,Wang Xiaobing1,Xu Youxuan1,Wu Yun1,Dong Ying1,Ouyang Gangfeng2

Affiliation:

1. National Anti-doping Laboratory; China Anti-Doping Agency; 1st Anding Road, ChaoYang District Beijing 100029 China

2. KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering; Sun Yat-sen University; Guangzhou 510275 China

Publisher

Wiley

Subject

Spectroscopy

Reference27 articles.

1. Estimation of tamoxifen metabolite concentrations in the blood of breast cancer patients through CYP2D6 genotype activity score;Wu;Breast Cancer Res. Treat.,2012

2. Tamoxifen and its metabolites cause acute vasorelaxation of aortic rings by inducing vasodilator prostanoid synthesis;Montenegro;J. Cardiovasc. Pharm.,2011

3. Pharmacogenomics of tamoxifen and aromatase inhibitors;Ingle;Cancer,2008

4. Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment;Borges;Clin. Pharmacol. Ther.,2006

5. Association of tamoxifen (TAM) and TAM metabolite concentrations with self-reported side effects of TAM in women with breast cancer;Gallicchio;Cancer Lett.,2004

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