The Potential Role of the J‐T peak Interval in Proarrhythmic Cardiac Safety: Current State of the Science From the American College of Clinical Pharmacology and the Cardiac Safety Research Consortium

Author:

Vicente Jose1ORCID,Strauss David G.2,Upreti Vijay V.3,Fossler Michael J.4,Sager Philip T.5,Noveck Robert6

Affiliation:

1. Division of Cardiovascular and Renal Products, Office of Drug Evaluation I, Office of New Drugs, Center for Drug Evaluation and ResearchUS Food and Drug Administration Silver Spring MD USA

2. Division of Applied Regulatory ScienceUS Food and Drug Administration Silver Spring MD USA

3. Clinical Pharmacology Oncology Therapeutic Area HeadClinical Pharmacology Modeling and SimulationAmgen South San Francisco CA USA

4. Clinical Operations & Quantitative SciencesTrevena, Inc. Chesterbrook PA USA

5. Stanford University Palo Alto CA USA

6. Duke Early Phase 1 Clinical Research Unit Durham NC USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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