Synthesis and evaluation of a18F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1receptor imaging-Reference-Cited by-同舟云学术

Synthesis and evaluation of a18F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1receptor imaging

Published:2016-06-09 Issue:9 Volume:59 Page:332-339
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J. Label Compd. Radiopharm

Author:

Ye Jiajun¹,Wang Xia¹,Deuther-Conrad Winnie²,Zhang Jinming³,Li Jianzhou¹,Zhang Xiaojun³,Wang Liang¹,Steinbach Jörg²,Brust Peter²,Jia Hongmei¹

Affiliation:

1. Key Laboratory of Radiopharmaceuticals (Beijing Normal University), Ministry of Education, College of Chemistry; Beijing Normal University; Beijing 100875 China

2. Helmholtz-Zentrum Dresden-Rossendorf, Department of Neuroradiopharmaceuticals; Institute of Radiopharmaceutical Cancer Research; 04318 Leipzig Germany

3. Nuclear Medicine Department; Chinese PLA General Hospital; Beijing 100853 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference34 articles.

1. Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

2. Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

3. The Sigma Receptor as a Ligand-Regulated Auxiliary Potassium Channel Subunit

4. The pharmacology of sigma-1 receptors

5. Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders

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