Direct arterial injection of hyperpolarized 13 C-labeled substrates into rat tumors for rapid MR detection of metabolism with minimal substrate dilution-Reference-Cited by-同舟云学术

Direct arterial injection of hyperpolarized 13 C-labeled substrates into rat tumors for rapid MR detection of metabolism with minimal substrate dilution

Published:2017-02-12 Issue:6 Volume:78 Page:2116-2126
ISSN:0740-3194
Container-title:Magnetic Resonance in Medicine
language:en
Short-container-title:Magn. Reson. Med.

Author:

Reynolds Steven¹,Metcalf Stephen²,Cochrane Edward J.³,Collins Rebecca C.³,Jones Simon³,Paley Martyn N.J.¹,Tozer Gillian M.²

Affiliation:

1. Academic Unit of Radiology, Department of Infection, Immunity and Cardiovascular Disease; University of Sheffield; Sheffield United Kingdom

2. Tumour Microcirculation Group, Department of Oncology and Metabolism; University of Sheffield; Sheffield United Kingdom

3. Department of Chemistry, Dainton Building; University of Sheffield; Brook Hill Sheffield United Kingdom

Funder

Cancer Research UK

MRC and Department of Health (England)

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging

Reference32 articles.

1. Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research;Kurhanewicz;Neoplasia,2011

2. Real-time metabolic imaging;Golman;Proc Natl Acad Sci U S A,2006

3. A calibration-based approach to real-time in vivo monitoring of pyruvate C(1) and C(2) polarization using the JCC spectral asymmetry;Lau;NMR Biomed,2013

4. Measurement of arterial input function in hyperpolarized C-13 studies;Marjanska;Appl Magn Reson,2012

5. Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice;Zierhut;J Magn Reson,2010

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pharmacokinetic–Pharmacodynamic Analysis of pH-Responsive Doxorubicin-Releasing Micelles with Anticancer Activity;Molecular Pharmaceutics;2024-05-27

2. Magnetization Lifetimes Prediction and Measurements Using Long-Lived Spin States in Endogenous Molecules;Molecules;2020-11-24

3. Preclinical Applications of Magnetic Resonance Imaging in Oncology;Molecular Imaging in Oncology;2020

4. Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma;Cancer Research;2018-07-27

5. Real-time ex-vivo measurement of brain metabolism using hyperpolarized [1-13C]pyruvate;Scientific Reports;2018-06-22