Encoding microcarriers for biomedicine

Author:

Wei Xiaowei12ORCID,Shang Yixuan2,Zhu Yefei1,Gu Zhuxiao2,Zhang Dagan2

Affiliation:

1. Laboratory Medicine Center The Second Affiliated Hospital of Nanjing Medical University Nanjing China

2. Department of Clinical Laboratory Institute of Translational Medicine The Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing China

Abstract

AbstractHigh throughput biological analysis has become an important topic in modern biomedical research and clinical diagnosis. The flow encoding scheme based on the encoding microcarriers provides a feasible strategy for the multiplexed biological analysis. Different encoding characteristics invest the microcarriers with different encoding mechanisms. Biosensor analysis, drug screening, cell culture, and the construction and evaluation of bionic organ chips can be realized by decoding the microcarriers and quantifying the detection signal intensity. In this review, the encoding strategy of microcarriers was divided into the optical and non‐optical encoding approaches according to their encoding elements, and the research progress of the microcarrier encoding strategy was elaborated. Finally, we summarized the biomedical applications and predicted their future prospects.

Publisher

Wiley

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