Nirmatrelvir combined with ritonavir for preventing and treating COVID-19

Author:

Reis Stefanie1,Metzendorf Maria-Inti2,Kuehn Rebecca3,Popp Maria1,Gagyor Ildiko4,Kranke Peter1,Meybohm Patrick1,Skoetz Nicole5,Weibel Stephanie1

Affiliation:

1. Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine; University Hospital Würzburg; Würzburg Germany

2. Cochrane Metabolic and Endocrine Disorders Group; Institute of General Practice, Medical Faculty of the Heinrich-Heine University Düsseldorf; Düsseldorf Germany

3. Department of Clinical Sciences; Liverpool School of Tropical Medicine; Liverpool UK

4. Department of General Practice; University Hospital Würzburg; Würzburg Germany

5. Cochrane Haematology, Department of Internal Medicine, Faculty of Medicine and University Hospital Cologne; Center for Integrated Oncology, University of Cologne; Cologne Germany

Publisher

Wiley

Subject

Pharmacology (medical)

Reference113 articles.

1. Oral nirmatrelvir for high-risk, nonhospitalized adults with COVID-19;Hammond;New England Journal of Medicine,2022

2. Norisuke K jRCT2031210267: A study of PF-07321332/ritonavir in nonhospitalized high risk adult participants with COVID-19 jrct.niph.go.jp/en-latest-detail/jRCT2031210267

3. 2021-002895-38: A phase 2/3 efficacy and safety study of PF-07321332 /ritonavir in nonhospitalized high risk adult participants with COVID 19 clinicaltrialsregister.eu/ctr-search/search?query=eudract_number:2021-002895-38

4. NCT04960202: EPIC-HR: study of oral PF-07321332/ritonavir compared with placebo in nonhospitalized high risk adults with COVID-19 clinicaltrials.gov/ct2/show/NCT04960202

5. Cautious optimism and considerations for health providers and patients: oral antiviral for early treatment of high-risk patients and vaccines for prevention of COVID-19;Caceres;American Journal of Medicine,2022

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