Rapid isolation and characterization of crocins, picrocrocin, and crocetin from saffron using centrifugal partition chromatography and LC-MS

Author:

Karkoula Evangelia12,Angelis Apostolis3,Koulakiotis Nikolaos-Stavros2,Gikas Evangelos4,Halabalaki Maria3ORCID,Tsarbopoulos Anthony12,Skaltsounis Alexios-Leandros3

Affiliation:

1. Medical School; Department of Pharmacology; National and Kapodistrian University of Athens; Athens Greece

2. Bioanalytical Department; GAIA Research Center, The Goulandris Natural History Museum; Kifissia Greece

3. Division of Pharmacognosy and Natural Products Chemistry; Department of Pharmacy; National and Kapodistrian University of Athens; Athens Greece

4. Division of Pharmaceutical Chemistry; Department of Pharmacy; National and Kapodistrian University of Athens; Athens Greece

Funder

TreatAD

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Reference40 articles.

1. HPLC quantification of major active components from 11 different saffron (Crocus sativus L.) sources;Caballero-Ortega;Food Chem,2007

2. Development and validation of HPLC method for determination of crocetin, a constituent of saffron, in human serum samples;Mohammadpour;Iran. J. Basic Med. Sci.,2013

3. The effective study of aqueous extract of Crocus sativus Linn.(Saffron) in depressed mice;Sunanda;Int. J. Pharm. Tech. Res.,2014

4. Crocins, the active constituents of Crocus sativus L., counteracted ketamine-induced behavioural deficits in rats;Georgiadou;Psychopharmacology,2014

5. Saffron as a source of novel acetylcholinesterase inhibitors: molecular docking and in vitro enzymatic studies;Geromichalos;J. Agric. Food Chem.,2012

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