Identification of a nuclear localization signal and importin beta members mediating NUAK1 nuclear import inhibited by oxidative stress-Reference-Cited by-同舟云学术

Identification of a nuclear localization signal and importin beta members mediating NUAK1 nuclear import inhibited by oxidative stress

Published:2019-05-15 Issue:9 Volume:120 Page:16088-16107
ISSN:0730-2312
Container-title:Journal of Cellular Biochemistry
language:en
Short-container-title:J Cell Biochem

Author:

Palma Mario¹,Riffo Elizabeth N.¹,Suganuma Tamaki²,Washburn Michael P.²³,Workman Jerry L.²,Pincheira Roxana¹,Castro Ariel F.¹^ORCID

Affiliation:

1. Departamento de Bioquímica y Biología Molecular, Laboratorio de Transducción de Señales y Cáncer, Facultad Cs. Biológicas Universidad de Concepción Concepción Chile

2. Stowers Institute for Medical Research Kansas City Missouri

3. Department of Pathology and Laboratory Medicine The University of Kansas Medical Center Kansas City Kansas

Funder

Fondo Nacional de Desarrollo Científico y Tecnológico

National Institutes of General Medical Sciences

Regular Fondecyt

CONICYT Scholarships

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcb.28890

Reference50 articles.

1. LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

2. The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation

3. The regulation and function of mammalian AMPK-related kinases

4. ARK5 promotes glioma cell invasion, and its elevated expression is correlated with poor clinical outcome

5. NUAK1 (ARK5) Is Associated with Poor Prognosis in Ovarian Cancer

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