Dose‐Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs-Reference-Cited by-同舟云学术

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Dose‐Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs

Published:2020-01 Issue:4 Volume:107 Page:1004-1013
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Mori Daiki¹,Kimoto Emi²,Rago Brian²,Kondo Yusuke¹,King‐Ahmad Amanda²,Ramanathan Ragu²,Wood Linda S.³,Johnson Jillian G.³,Le Vu H.⁴,Vourvahis Manoli⁵,David Rodrigues A.²,Muto Chieko⁶,Furihata Kenichi⁷,Sugiyama Yuichi⁸,Kusuhara Hiroyuki¹

Affiliation:

1. Laboratory of Molecular Pharmacokinetics Graduate School of Pharmaceutical Sciences The University of Tokyo Tokyo Japan

2. ADME Sciences, Medicine Design Pfizer Inc. Groton Connecticut USA

3. Clinical Pharmacogenomics Lab Early Clinical Development Pfizer Inc. Groton Connecticut USA

4. Biostatistics Pfizer Inc. Collegeville PA USA

5. Clinical Pharmacology Pfizer Inc. New York New York USA

6. Pfizer Inc. Tokyo Japan

7. P‐One Clinic Keikokai Medical Corp Tokyo Japan

8. RIKEN Innovation Center Research Cluster for Innovation RIKEN Kanagawa Japan

Funder

Pfizer

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1695

Reference38 articles.

1. Comparing Various In Vitro Prediction Criteria to Assess the Potential of a New Molecular Entity to Inhibit Organic Anion Transporting Polypeptide 1B1

2. The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?

3. Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium

4. Endogenous Biomarkers to Assess Drug-Drug Interactions by Drug Transporters and Enzymes

5. Biomarkers for In Vivo Assessment of Transporter Function

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3. The influence of OATP2B1 and atorvastatin on coproporphyrin isomers in rats;Journal of Pharmacological Sciences;2023-11

4. Utilization of OATP1B Biomarker Coproporphyrin‐I to Guide Drug–Drug Interaction Risk Assessment: Evaluation by the Pharmaceutical Industry;Clinical Pharmacology & Therapeutics;2023-10-11

5. Various effects of repeated rifampin dosing on coproporphyrin levels in humans;Clinical and Translational Science;2023-09-19

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