Interspeciesin vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560-Reference-Cited by-同舟云学术

Interspeciesin vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560

Published:2006 Issue:6 Volume:41 Page:771-780
ISSN:1076-5174
Container-title:Journal of Mass Spectrometry
language:en
Short-container-title:J. Mass Spectrom.

Author:

Bateman Kevin P.,Trimble Laird,Chauret Nathalie,Silva Jose,Day Stephen,Macdonald Dwight,Dube Daniel,Gallant Michel,Mastracchio Anthony,Perrier Helene,Girard Yves,Nicoll-Griffith Deborah

Publisher

Wiley

Subject

Spectroscopy

Reference20 articles.

1. The Multienzyme PDE4 Cyclic Adenosine Monophosphate–Specific Phosphodiesterase Family: Intracellular Targeting, Regulation, and Selective Inhibition by Compounds Exerting Anti-inflammatory and Antidepressant Actions

2. Preferential Inhibition of T Helper 1, but Not T Helper 2, Cytokines in Vitro by L-826,141 [4-{2-(3,4-Bisdifluromethoxyphenyl)-2-{4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl}-3-methylpyridine-1-oxide], a Potent and Selective Phosphodiesterase 4 Inhibitor

3. Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma

4. PDE4 inhibition and a corticosteroid in chronically antigen exposed conscious guinea-pigs

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