The effects of proliferation and DNA damage on hematopoietic stem cell function determine aging
Author:
Affiliation:
1. School of Biology, Indian Institute of Science Education and Research; Thiruvananthapuram India 695016
Funder
Indian Institute of Science Education and Research, Thiruvananthapuram (IISER TVM)
Publisher
Wiley
Subject
Developmental Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/dvdy.24388/fullpdf
Reference115 articles.
1. Biology of dendritic cells in aging;Agrawal;J Clin Immunol,2008
2. Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis;Akashi;Blood,2003
3. Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation;Allsopp;Blood,2003
4. Hematopoietic stem cell aging is uncoupled from p16 INK4A-mediated senescence;Attema;Oncogene,2009
5. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging;Beerman;Cell Stem Cell,2013
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