Determination of tautomeric preference of fenobam in solution by high‐resolution NMR spectroscopy-Reference-Cited by-同舟云学术

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Determination of tautomeric preference of fenobam in solution by high‐resolution NMR spectroscopy

Published:2021-01-14 Issue:6 Volume:59 Page:641-647
ISSN:0749-1581
Container-title:Magnetic Resonance in Chemistry
language:en
Short-container-title:Magn Reson Chem

Author:

Sha Xuming¹,Chen Shaodong²,Zheng Xiaojing¹,Ye Xin²,Zhang Hailu²,Huang Shaohua¹³^ORCID

Affiliation:

1. Institute of Drug Discovery Technology Ningbo University Ningbo China

2. Suzhou Institute of Nano‐Tech and Nano‐Bionics (SINANO) Chinese Academy of Sciences Suzhou China

3. Qian Xuesen Collaborative Research Center of Astrochemistry and Space Life Sciences Ningbo University Ningbo China

Funder

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Higher Education Discipline Innovation Project

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Materials Science,General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mrc.5127

Reference26 articles.

1. Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity

2. A pilot open label, single dose trial of fenobam in adults with fragile X syndrome

3. The Metabotropic Glutamate Receptor Subtype 5 Antagonist Fenobam Is Analgesic and Has Improved in Vivo Selectivity Compared with the Prototypical Antagonist 2-Methyl-6-(phenylethynyl)-pyridine

4. Fmr1 KO and Fenobam Treatment Differentially Impact Distinct Synapse Populations of Mouse Neocortex

5. The anxiolytic and analgesic properties of fenobam, a potent mGlu5 receptor antagonist, in relation to the impairment of learning

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