Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity-Reference-Cited by-同舟云学术

Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity

Published:2005-07-22 Issue:2 Volume:315 Page:711-721
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Porter Richard H. P.,Jaeschke Georg,Spooren Will,Ballard Theresa M.,Büttelmann Bernd,Kolczewski Sabine,Peters Jens-Uwe,Prinssen Eric,Wichmann Jürgen,Vieira Eric,Mühlemann Andreas,Gatti Silvia,Mutel Vincent,Malherbe Pari

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference40 articles.

1. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison

2. Scintillation proximity assay of inositol phosphates in cell extracts: High-throughput measurement of G-protein-coupled receptor activation

3. Chronic But Not Acute Treatment with a Metabotropic Glutamate 5 Receptor Antagonist Reverses the Akinetic Deficits in a Rat Model of Parkinsonism

4. Anxiolytic-like activity of the mGluR5 antagonist MPEPA comparison with diazepam and buspirone

5. The Behavioral Profile of the Potent and Selective mGlu5 Receptor Antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in Rodent Models of Anxiety

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