Mechanistic Physiologically Based Pharmacokinetic Models in Development of Therapeutic Monoclonal Antibodies

Author:

Cao Yanguang12,Jusko William J.1

Affiliation:

1. State University of New York at Buffalo; Buffalo NY USA

2. The University of North Carolina at Chapel Hill; Chapel Hill NC USA

Publisher

John Wiley & Sons, Inc.

Reference69 articles.

1. Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations

2. Physiologically based pharmacokinetics joined with in vitro-in vivo extrapolation of ADME: a marriage under the arch of systems pharmacology;Rostami-Hodjegan;Clin Pharmacol Ther,2012

3. An industrial perspective on contemporary applications of PBPK models in drug discovery and development;Smith;Biopharm Drug Dispos,2012

4. The utility of modeling and simulation in drug development and regulatory review;Huang;J Pharm Sci,2013

5. Search: physiologically-based pharmacokinetic model [ti] and yyyy[PDAT]: yyyy[PDAT]. Or physiologically-based pharmacokinetics [ti] and antibody[ab] 1946 http://pubmed.gov/

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