Dimethylbutyrylated Dibenzocyclooctadiene Lignans from the Fruits of Schisandra cauliflora Inhibit NO Production in LPS‐Activated RAW264.7 Cells

Author:

Yen Pham Hai1,Hoang Nguyen Huy1,Nhiem Nguyen Xuan1,Thanh Huong Phan Thi1,Dung Duong Thi1,Cuc Nguyen Thi1,Cuong Nguyen The2,Thanh Bui Van2,Tai Bui Huu1,Kiem Phan Van1ORCID

Affiliation:

1. Institute of Marine Biochemistry Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet, Cau Giay Hanoi 10072 Vietnam

2. Institute of Ecology and Biological Resources VAST, 18 Hoang Quoc Viet, Cau Giay Hanoi 10072 Vietnam

Abstract

AbstractFrom the fruits of Schisandra cauliflora, five new dimethylbutyrylated dibenzocyclooctadiene lignans, named schisandracaurins A−E, were isolated using separation and chromatographic techniques. Their structures were determined by extensive analyses of HR‐ESI‐MS, NMR, and ECD spectra. The schisandracaurins A−E potentially inhibited NO production in LPS‐activated RAW264.7 cells with their IC50 values from 21.4 to 30.3 μM.

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3