A Comprehensive Review of the Diverse Spectrum Activity of 1,2,3‐Triazole‐linked Isatin Hybrids

Author:

Rohila Yajat1ORCID,Sebastian Sharol1ORCID,Ansari Azaj1ORCID,Kumar Deepak2,Mishra D. K.3,Gupta Manoj K.1ORCID

Affiliation:

1. Department of Chemistry School of Basic Sciences Department of Chemistry Central University of Haryana. Mahendergarh-123031 Haryana India

2. Department of Pharmaceutical Chemistry School of Pharmaceutical Sciences Shoolini University Solan 173229 Himachal Pradesh India

3. Department of Chemistry Shri Ramswaroop Memorial College of Engineering & Management Lucknow 226028 Uttar Pradesh India

Abstract

AbstractHeterocyclic compounds containing 1,2,3‐triazole and isatin as core structures have emerged as promising drug candidates due to their diverse biological activities such as anti‐cancer, antifungal, antimicrobial, antitumor, anti‐epileptic, antiviral, and more. The presence of 1,2,3‐triazoles and isatin heterocycles in these hybrids, both individually known for their medicinal significance, has increasingly piqued the interest of drug discovery researchers, as they seek to delve deeper into their extensive pharmacological potential for enhancing therapeutic efficacy. Moreover, these hybrid compounds are synthetically accessible using readily available materials. Therefore, there is a pressing need to provide a comprehensive overview of the existing knowledge in this field, offering valuable insights to readers and paving the way for the discovery of novel 1,2,3‐triazole‐linked isatin hybrids with therapeutic potential.

Publisher

Wiley

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