Design, Synthesis and Anticancer Activity of Novel Steroidal Derivatives with D‐Ring Fused or Substituted N‐Heterocyclic Systems-Reference-Cited by-同舟云学术

Design, Synthesis and Anticancer Activity of Novel Steroidal Derivatives with D‐Ring Fused or Substituted N‐Heterocyclic Systems

Published:2022-09-16 Issue:10 Volume:19 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chemistry & Biodiversity

Author:

Li Xiao‐San¹²^ORCID,Yang Mao‐Xun¹³,Luo Yu‐Hao¹,Zhan He‐Hui¹,Chen Mei‐Fang²,Huang Yong‐Mei²,Liu Li¹,Yang Xue‐Mei¹

Affiliation:

1. Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs Key Laboratory of Research and Development of New Medical Materials of Guangdong Medical University School of Pharmacy Guangdong Medical University Dongguan 523808 P. R. China

2. Marine Biomedical Research Institute the Key Lab of Zhanjiang for R&D Marine Microbial Resources in the Beibu Gulf Rim Guangdong Medical University Zhanjiang 524023 P. R. China

3. Marine Chinese Medicine Branch National Engineering Research Center for Modernization of Traditional Chinese Medicine Zhanjiang 524023 P. R. China

Funder

Traditional Chinese Medicine Bureau of Guangdong Province

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202200648

Reference23 articles.

1. Synthesis of monomeric and dimeric steroids containing [1,2,4]triazolo[1,5-a]pyrimidines

2. Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists

3. Efficient construction of novel D-ring modified steroidal dienamides and their cytotoxic activities

4. A novel [1,2,4] triazolo [1,5-a] pyrimidine-based phenyl-linked steroid dimer: Synthesis and its cytotoxic activity

5. Novel 17-Azolyl Steroids, Potent Inhibitors of Human Cytochrome 17α-Hydroxylase-C17,20-lyase (P45017α): Potential Agents for the Treatment of Prostate Cancer

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