Innovative Encapsulation Strategies for Food, Industrial, and Pharmaceutical Applications

Author:

Aanniz Tarik1,El Omari Nasreddine23,Elouafy Youssef4,Benali Taoufiq5,Zengin Gokhan6ORCID,Khalid Asaad78,Abdalla Ashraf N.9,Sakran Ashraf M.10,Bouyahya Abdelhakim11

Affiliation:

1. Biotechnology Laboratory (MedBiotech) Bioinova Research Center Rabat Medical and Pharmacy School Mohammed V University in Rabat Rabat 10100 Morocco

2. High Institute of Nursing Professions and Health Techniques of Tetouan Tetouan Morocco

3. Laboratory of Histology Embryology and Cytogenetic Faculty of Medicine and Pharmacy Mohammed V University in Rabat Rabat 10100 Morocco

4. Laboratory of Materials Nanotechnology and Environment LMNE Faculty of Sciences Mohammed V University in Rabat Rabat BP 1014 Morocco

5. Environment and Health Team, Polydisciplinary Faculty of Safi Cadi Ayyad University Marrakech 46030 Morocco

6. Department of Biology Science Faculty Selcuk University 42130 Konya Turkey

7. Substance Abuse and Toxicology Research Center Jazan University P.O. Box: 114 Jazan 45142 Saudi Arabia

8. Medicinal and Aromatic Plants and Traditional Medicine Research Institute National Center for Research P. O. Box 2404 Khartoum Sudan

9. Department of Pharmacology and Toxicology College of Pharmacy Umm Al-Qura University Makkah 21955 Saudi Arabia

10. Department of Anatomy Faculty of Medicine Umm Alqura University Makkah 21955 Saudi Arabia

11. Laboratory of Human Pathologies Biology Department of Biology Faculty of Sciences Mohammed V University in Rabat Rabat 10106 Morocco

Abstract

AbstractBioactive metabolites obtained from fruits and vegetables as well as many drugs have various capacities to prevent or treat various ailments. Nevertheless, their efficiency, in vivo, encounter many challenges resulting in lower efficacy as well as different side effects when high doses are used resulting in many challenges for their application. Indeed, demand for effective treatments with no or less unfavorable side effects is rising. Delivering active molecules to a particular site of action within the human body is an example of targeted therapy which remains a challenging field. Developments of nanotechnology and polymer science have great promise for meeting the growing demands of efficient options. Encapsulation of active ingredients in nano‐delivery systems has become as a vitally tool for protecting the integrity of critical biochemicals, improving their delivery, enabling their controlled release and maintaining their biological features. Here, we examine a wide range of nano‐delivery techniques, such as niosomes, polymeric/solid lipid nanoparticles, nanostructured lipid carriers, and nano‐emulsions. The advantages of encapsulation in targeted, synergistic, and supportive therapies are emphasized, along with current progress in its application. Additionally, a revised collection of studies was given, focusing on improving the effectiveness of anticancer medications and addressing the problem of antimicrobial resistance. To sum up, this paper conducted a thorough analysis to determine the efficacy of encapsulation technology in the field of drug discovery and development.

Publisher

Wiley

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