FRAME Study: The Foundation Effect of Building Bone With 1 Year of Romosozumab Leads to Continued Lower Fracture Risk After Transition to Denosumab-Reference-Cited by-同舟云学术

FRAME Study: The Foundation Effect of Building Bone With 1 Year of Romosozumab Leads to Continued Lower Fracture Risk After Transition to Denosumab

Published:2018-05-17 Issue:7 Volume:33 Page:1219-1226
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Cosman Felicia¹²,Crittenden Daria B³,Ferrari Serge⁴,Khan Aliya⁵,Lane Nancy E⁶,Lippuner Kurt⁷,Matsumoto Toshio⁸,Milmont Cassandra E³,Libanati Cesar⁹,Grauer Andreas³

Affiliation:

1. Helen Hayes Hospital; West Haverstraw; NY USA

2. College of Physician and Surgeons; Columbia University; New York NY USA

3. Amgen Inc.; Thousand Oaks; CA USA

4. Geneva University Hospital; Geneva; Switzerland

5. Department of Medicine; McMaster University; Hamilton ON Canada

6. Center for Musculoskeletal Health; UC Davis Medical Center; UC Davis; Sacramento CA USA

7. Department of Osteoporosis; Bern University Hospital; University of Bern; Switzerland

8. University of Tokushima; Tokushima; Japan

9. UCB Pharma; Brussels; Belgium

Funder

Amgen Inc.

UCB Pharma

Astellas Pharma

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jbmr.3427/fullpdf

Reference38 articles.

1. Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody;Padhi;J Bone Miner Res,2011

2. Romosozumab in postmenopausal women with low bone mineral density;McClung;N Engl J Med,2014

3. Progressive increases in bone mass and bone strength in an ovariectomized rat model of osteoporosis after 26 weeks of treatment with a sclerostin antibody;Li;Endocrinology,2014

4. Romosozumab (sclerostin antibody) improves bone mass and bone strength in ovariectomized cynomolgus monkeys after 12 months of treatment;Jolette;J Bone Miner Res,2015

5. Effects of romosozumab on remodeling and bone strength at the distal radius in ovariectomized cynomolgus monkeys;Ominsky;J Bone Miner Res,2016

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