The Potential of Indole Alkaloids in Bone Health and Osteoporosis Management-Reference-Cited by-同舟云学术

The Potential of Indole Alkaloids in Bone Health and Osteoporosis Management

Published:2024-09-10 Issue:18 Volume:14 Page:8124
ISSN:2076-3417
Container-title:Applied Sciences
language:en
Short-container-title:Applied Sciences

Author:

Caruso Anna¹,Caira Virginia²,El-Kashef Hussein³⁴^ORCID,Saturnino Carmela¹^ORCID

Affiliation:

1. Department of Science, University of Basilicata, Viale dell’Ateneo Lucano 10, 85100 Potenza, Italy

2. U.O.S. Reumatologia, P.O. of Castrovillari, ASP Cosenza, 87012 Castrovillari, Italy

3. Faculty of Science, Assiut University, Assiut 71516, Egypt

4. Faculty of Pharmacy, Sphinx University, New Assiut 71515, Egypt

Abstract

Indole alkaloids, a class of plant-derived nitrogen-containing compounds, have emerged as promising candidates for osteoporosis treatment. Their favorable biocompatibility profile demonstrated efficacy in preclinical models, and low reported toxicity make them attractive alternatives to existing therapies. This review focuses on the therapeutic potential of specific indole alkaloids, including vindoline, rutaecarpine, harmine, and its derivatives, in promoting bone health and managing osteoporosis.

Publisher

MDPI AG

Link

https://www.mdpi.com/2076-3417/14/18/8124/pdf

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