Synthesis and characterization of novel radiofluorinated probes for positron emission tomography imaging of monoamine oxidase B

Author:

Yoshimoto Mitsuyoshi12,Hirata Masahiko1,Kagawa Shinya13,Magata Yasuhiro45,Ohmomo Yoshiro1,Temma Takashi1ORCID

Affiliation:

1. Department of Biofunctional Analysis; Osaka University of Pharmaceutical Sciences; Takatsuki Japan

2. Division of Functional Imaging, Exploratory Oncology Research & Clinical Trial Center; National Cancer Center; Kashiwa Japan

3. Division of PET Imaging; Shiga Medical Center Research Institute; Moriyama Japan

4. Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine; Kyoto University; Kyoto Japan

5. Department of Molecular Imaging, Institute for Medical Photonics Research, Preeminent Medial Photonics Education and Research Center; Hamamatsu University School of Medicine; Hamamatsu Japan

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference24 articles.

1. Localization of MAO-A and MAO-B in human brain: a step in understanding the therapeutic action of L-deprenyl;Riederer;Adv Neurol,1987

2. Interactions of monoamine oxidase with substrates and inhibitors;Dostert;Med Res Rev,1989

3. Localization of monoamine oxidase in rat liver mitochondria;Greenawalt;Adv Biochem Psychopharmacol,1972

4. The covalently-bound flavin of hepatic monoamine oxidase. 1. Isolation and sequence of a flavin peptide and evidence for binding at the 8α position;Kearney;Eur J Biochem,1971

5. Increased binding of 3H-L-deprenyl in spinal cords from patients with amyotrophic lateral sclerosis as demonstrated by autoradiography;Aquilonius;J Neural Transm Gen Sect,1992

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