Novel Mechanism of Fatty Acid Sensing in Enteroendocrine Cells: Specific Structures in Oxo-Fatty Acids Produced by Gut Bacteria Are Responsible for CCK Secretion in STC-1 Cells via GPR40-Reference-Cited by-同舟云学术

Novel Mechanism of Fatty Acid Sensing in Enteroendocrine Cells: Specific Structures in Oxo-Fatty Acids Produced by Gut Bacteria Are Responsible for CCK Secretion in STC-1 Cells via GPR40

Published:2018-07-25 Issue:19 Volume:62 Page:1800146
ISSN:1613-4125
Container-title:Molecular Nutrition & Food Research
language:en
Short-container-title:Mol. Nutr. Food Res.

Author:

Hira Tohru¹,Ogasawara Shono²,Yahagi Asuka²,Kamachi Minami²,Li Jiaxin³,Nishimura Saki⁴,Sakaino Masayoshi⁴,Yamashita Takatoshi⁴,Kishino Shigenobu⁵,Ogawa Jun⁵,Hara Hiroshi¹

Affiliation:

1. Research Faculty of Agriculture; Hokkaido University; Sapporo 060-8589 Japan

2. Graduate School of Agriculture; Hokkaido University; Sapporo 060-8589 Japan

3. School of Agriculture; Hokkaido University; Sapporo 060-8589 Japan

4. Fundamental Research Laboratory, Research and Development Division; J-Oil Mills, Inc.; Yokohama 230-0053 Japan

5. Graduate School of Agriculture; Kyoto University; Kyoto 606-8502 Japan

Publisher

Wiley

Subject

Food Science,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/mnfr.201800146/fullpdf

Reference35 articles.

1. Enteroendocrine Cells: Chemosensors in the Intestinal Epithelium

2. Pharmacology and physiology of gastrointestinal enteroendocrine cells

3. Cholecystokinin

4. Cholecystokinin—From Local Gut Hormone to Ubiquitous Messenger

5. Fatty acids stimulate cholecystokinin secretion via an acyl chain length-specific, Ca2+-dependent mechanism in the enteroendocrine cell line STC-1

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