Rational Design, Structure–Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants

Author:

Eichhorn Stephanie1,Hörschläger Angelika1,Steiner Markus1,Laimer Josef1,Jensen Bettina M2,Versteeg Serge A3,Pablos Isabel1,Briza Peter1,Jongejan Laurian3,Rigby Neil4,Asturias Juan A5,Portolés Antonio6,Fernandez‐Rivas Montserrat7,Papadopoulos Nikolaos G89,Mari Adriano1011,Poulsen Lars K2,Lackner Peter1,Ree Ronald312,Ferreira Fatima1,Gadermaier Gabriele1ORCID

Affiliation:

1. Department of BiosciencesUniversity of Salzburg Hellbrunnerstraße 34 5020 Salzburg Austria

2. Allergy Clinic, Dept. 22Herlev‐Gentofte Hospital Kildegaardsvej 28 2900 Hellerup Denmark

3. Department of Experimental ImmunologyAmsterdam University Medical Centers Meibergdreef 9 1105AZ Amsterdam The Netherlands

4. Food & Health ProgrammeInst. of Food Research Norwich Norfolk NR4 7UQ United Kingdom

5. R&D DepartmentROXALL GroupParque Científico y Tecnológico de Bizkaia Edif. 401 48170 Zamudio Spain

6. Department of Clinical PharmacologyHospital Clinico San Carlos c/ Prof. Martín Lagos s/n 28040 Madrid Spain

7. Department of AllergyHospital Clinico San Carlos c/ Prof. Martín Lagos s/n 28040 Madrid Spain

8. Division of Infection, Immunity & Respiratory MedicineUniversity of ManchesterRoyal Manchester Children's Hospital Manchester M13 9WL United Kingdom

9. Allergy Dpt, 2nd Pediatric Clinic, University of Athens 41, Fidippidou Athens 115 27 Greece

10. Center of Molecular AllergologyIDI Via dei Monti di Creta 104 ZIP 00167 Rome Italy

11. Associated Centers for Molecular Allergology Via Portuense 700 ZIP 00149 Rome Italy

12. Department of OtorhinolaryngologyAmsterdam University Medical Centers Meibergdreef 9 1105AZ Amsterdam The Netherlands

Funder

FP7 Health

Publisher

Wiley

Subject

Food Science,Biotechnology

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