Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer

Author:

Kahremany Shirin1,Babaev Ilana1,Hasin Pinhas1,Tamir Tigist Y.2,Ben-Zur Tali3,Cohen Guy4,Jiang Zhengyu5,Weintraub Sagiv1,Offen Daniel3,Rahimipour Shai1,Major M. Ben2,Senderowitz Hanoch1,Gruzman Arie1ORCID

Affiliation:

1. Department of Chemistry; Faculty of Exact Sciences; Bar-Ilan University; Ramat Gan 5290002 Israel

2. Department of Pharmacology; and the Lineberger Comprehensive Cancer Center; University of North Carolina at Chapel Hill; Chapel Hill NC 27599 USA

3. Felsenstein Medical Research Center; Sackler Faculty of Medicine; Tel-Aviv University; Rabin Medical Center-Beilinson Campus Petah Tikva 49100 Israel

4. The Skin Research Institute; The Dead Sea & Arava Science Center; Tamar Regional Council; Dead Sea Mobile Post 86910 Israel

5. Jiangsu Key Laboratory of Drug Design and Optimization; Department of Medicinal Chemistry; School of Pharmacy; China Pharmaceutical University Nanjing; Jiangsu 210008 P. R. China

Funder

Bar-Ilan University new faculty grant

Bar-Ilan University, Ramat-Gan and Rabin Medical Center Collaborative Grant in Biomedical Research with D. Offen

Wolf Foundation

Publisher

Wiley

Subject

General Chemistry

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