Oridonin ameliorates acetaminophen‐induced acute liver injury through ATF4/PGC‐1α pathway-Reference-Cited by-同舟云学术

Oridonin ameliorates acetaminophen‐induced acute liver injury through ATF4/PGC‐1α pathway

Published:2022-12-26 Issue:2 Volume:84 Page:211-225
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Development Research

Author:

Yu Dongsheng¹^ORCID,Li Jiye²³,Wang Yu¹,Guo Danfeng²³,Zhang Xiaodan²³,Chen Mingming⁴⁵,Zhou Zheng¹

Affiliation:

1. Department of Chinese Medicine The First Affiliated Hospital of Zhengzhou University Zhengzhou China

2. Henan Research Centre for Organ Transplantation Zhengzhou China

3. Henan Key Laboratory for Digestive Organ Transplantation Zhengzhou China

4. Chinese Medicine Modernization and Big Data Research Center Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine Nanjing China

5. Department of Neurology Yale University School of Medicine New Haven Connecticut USA

Publisher

Wiley

Subject

Drug Discovery

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.22024

Reference52 articles.

1. Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase

2. 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes

3. ER stress and ASK1-JNK activation contribute to oridonin-induced apoptosis and growth inhibition in cultured human hepatoblastoma HuH-6 cells

4. The ER stress sensor inositol-requiring enzyme 1α in Kupffer cells promotes hepatic ischemia-reperfusion injury

5. Reversal of bioenergetics dysfunction by diphenyl diselenide is critical to protection against the acetaminophen-induced acute liver failure

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