Effective mRNA Protection by Poly( l ‐ornithine) Synergizes with Endosomal Escape Functionality of a Charge‐Conversion Polymer toward Maximizing mRNA Introduction Efficiency

Author:

Dirisala Anjaneyulu1,Uchida Satoshi12ORCID,Li Junjie1,Van Guyse Joachim F. R.1,Hayashi Kotaro1,Vummaleti Sai V. C.3,Kaur Sarandeep4,Mochida Yuki1,Fukushima Shigeto1,Kataoka Kazunori1

Affiliation:

1. Innovation Center of NanoMedicine (iCONM) Kanagawa Institute of Industrial Promotion 3‐25‐14 Tonomachi, Kawasaki‐ku Kawasaki 210‐0821 Japan

2. Medical Chemistry Graduate School of Medical Science Kyoto Prefectural University of Medicine 1–5 Shimogamohangi‐cho Sakyo‐ku Kyoto 606‐0823 Japan

3. Institute of High Performance Computing Agency for Science Technology and Research 1 Fusionopolis Way 16‐6 Connexis 138632 Singapore

4. Institute of Bioanalytical Chemistry Faculty of Chemistry and Mineralogy Universität Leipzig Johannisallee 29 Leipzig 04103 Germany

Funder

Center of Innovation Program

Japan Science and Technology Agency

Japan Agency for Medical Research and Development

Publisher

Wiley

Subject

Materials Chemistry,Polymers and Plastics,Organic Chemistry

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