Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery

Author:

Tanaka Hiroki1ORCID,Takahashi Tatsunari1,Konishi Manami1,Takata Nae1,Gomi Masaki1,Shirane Daiki1,Miyama Ryo1,Hagiwara Shinya1,Yamasaki Yuki1,Sakurai Yu1,Ueda Keisuke2,Higashi Kenjirou2,Moribe Kunikazu2,Shinsho Eiji3,Nishida Ruka3,Fukuzawa Kaori34,Yonemochi Etsuo3,Okuwaki Koji5,Mochizuki Yuji45,Nakai Yuta6,Tange Kota6,Yoshioka Hiroki6,Tamagawa Shinya6,Akita Hidetaka1ORCID

Affiliation:

1. Laboratory of DDS Design and Drug Disposition Graduate School of Pharmaceutical Sciences Chiba University 1‐8‐1 Inohana, Chuo‐ku Chiba Chiba 260‐0856 Japan

2. Laboratory of Pharmaceutical Technology Graduate School of Pharmaceutical Sciences Chiba University 1‐8‐1, Inohana, Chuo‐ku Chiba Chiba 260‐0856 Japan

3. School of Pharmacy and Pharmaceutical Sciences Hoshi University 2‐4‐41, Ebara, Shinagawa Tokyo 145‐8501 Japan

4. Institute of Industrial Science The University of Tokyo 4‐6‐1 Komaba, Meguro‐ku Tokyo 153‐8505 Japan

5. Department of Chemistry and Research Center for Smart Molecules Faculty of Science Rikkyo University Toshima Tokyo 171‐8501 Japan

6. DDS Research Laboratory NOF CORPORATION 3‐3 Chidori‐cho, Kawasaki‐ku Kawasaki Kanagawa 210‐0865 Japan

Funder

Japan Society for the Promotion of Science

Chiba University

Japan Science and Technology Agency

Asahi Glass Foundation

Core Research for Evolutional Science and Technology

Publisher

Wiley

Subject

Electrochemistry,Condensed Matter Physics,Biomaterials,Electronic, Optical and Magnetic Materials

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